Catarina Pinto Reis
Contacts
E-mail: catarinareis[at]ff.ulisboa.pt
Professional networks
Curriculum
Research topics
- Drug delivery systems
- Food supplements and cosmetics
- In vivo efficacy and safety assessments
- Medical devices
- Methods of micro- and nanoencapsulation of drugs using animal models
- Pre-clinical toxicity assessment
- Regulatory affairs
- Therapeutic polymers
Biography
Catarina Pinto Reis is Assistant Professor with Habilitation at Faculty of Pharmacy (University of Lisbon, Lisbon, Portugal). She is a research member of IBEB and iMed.ULisboa. She is also an external consultant of INFARMED. She attended the University of Coimbra (Coimbra, Portugal) and graduated in Pharmaceutical Sciences. Her doctoral studies were also undertaken at the University of Coimbra with several important international collaborations where she developed an interest in advanced drug delivery systems. Those studies have been recognized through a number of national prizes. She finished her PhD in Pharmacy in 2008 and since then, she has continued to work in the drug delivery field.
Her research interests are focused on the development of new drug delivery systems, medical devices, therapeutic polymers, methods of micro- and nanoencapsulation of drugs, food supplements and cosmetics, targeted therapies, in vivo efficacy and safety assessments using animal models, pre-clinical toxicity assessment, regulatory affairs, etc. She is author or co-author of more than 100 papers, book chapters and inventor of patents.
Publications
Journal publications
(2023) The current role of cannabis and cannabinoids in health: A comprehensive review of their therapeutic potential, Life Sciences 329, p. 121838, Pergamon, doi:10.1016/j.lfs.2023.121838
(2023) Experimental Murine Models for Colorectal Cancer Research, Cancers 15(9), p. 2570, MDPI, doi:10.3390/cancers15092570
(2023) Marine Natural Products as Innovative Cosmetic Ingredients, Marine Drugs 21(3), p. 170, MDPI, doi:10.3390/md21030170
(2023) Nanoparticle-Based Treatment in Glioblastoma, Journal of Personalized Medicine 13(9), p. 1328, MDPI, doi:10.3390/jpm13091328
(2023) Edible Seaweeds Extracts: Characterization and Functional Properties for Health Conditions, Antioxidants 12(3), p. 684, MDPI, doi:10.3390/antiox12030684
(2023) Highlighted Advances in Therapies for Difficult-To-Treat Brain Tumours Such as Glioblastoma, Pharmaceutics 15(3), p. 928, MDPI, doi:10.3390/pharmaceutics15030928
(2023) Pluronic® F127 Hydrogel Containing Silver Nanoparticles in Skin Burn Regeneration: An Experimental Approach from Fundamental to Translational Research, Gels 9(3), p. 200, MDPI, doi:10.3390/gels9030200
(2023) Aplicação de várias técnicas analíticas para avaliação da qualidade de comprimidos vendidos no mercado informal em Luanda, Angola, RevSALUS - Revista Científica da Rede Académica das Ciências da Saúde da Lusofonia 5(Sup), p. 23-23, doi:10.51126/revsalus.v5isup.530
(2022) The role of HEIs in a Quadruple Helix collaboration for RIS3. White paper with policy recommendations, European Commission
(2022) How to Treat Melanoma? The Current Status of Innovative Nanotechnological Strategies and the Role of Minimally Invasive Approaches like PTT and PDT, Pharmaceutics 14(9), p. 1817, MDPI, doi:10.3390/pharmaceutics14091817
(2022) New iron(III) anti-cancer aminobisphenolate/phenanthroline complexes: Enhancing their therapeutic potential using nanoliposomes, International Journal of Pharmaceutics 623, p. 121925, Elsevier, doi:10.1016/j.ijpharm.2022.121925
(2022) Dehydroroyleanone as a Building Block for a Drug Delivery Platform Based on Self-Assembled Nanoparticles: Structural Studies and Chemical Modification, ACS Omega 7(48), p. 44180-44186, American Chemical Society, doi:10.1021/acsomega.2c05353
(2022) Therapeutic advances in wound healing, Journal of Dermatological Treatment 33(1), p. 2-22, Taylor & Francis, doi:10.1080/09546634.2020.1730296
(2022) Melanoma Management: From Epidemiology to Treatment and Latest Advances, Cancers 14(19), p. 4652, MDPI, doi:10.3390/cancers14194652
() Submicron particles of hyaluronic acid for treatment of osteoarthritis
(2022) Liposomal Formulations of a New Zinc(II) Complex Exhibiting High Therapeutic Potential in a Murine Colon Cancer Model, International Journal of Molecular Sciences 23(12), p. 6728, MDPI, doi:10.3390/ijms23126728
(2022) The Role of Rosmarinic Acid on the Bioproduction of Gold Nanoparticles as Part of a Photothermal Approach for Breast Cancer Treatment, Biomolecules 12(1), p. 71, MDPI, doi:10.3390/biom12010071
(2022) Metal Coordination and Biological Screening of a Schiff Base Derived from 8-Hydroxyquinoline and Benzothiazole, Pharmaceutics 14(12), p. 2583, MDPI, doi:10.3390/pharmaceutics14122583
(2022) Biological Thermal Performance of Organic and Inorganic Aerogels as Patches for Photothermal Therapy, Gels 8(8), p. 485, MDPI, doi:10.3390/gels8080485
(2022) Nanoformulation of Seaweed Eisenia bicyclis in Albumin Nanoparticles Targeting Cardiovascular Diseases: In Vitro and In Vivo Evaluation, Marine Drugs 20(10), p. 608, MDPI, doi:10.3390/md20100608
(2022) Current Insights and Progress in the Clinical Management of Head and Neck Cancer, Cancers 14(24), p. 6079, MDPI, doi:10.3390/cancers14246079
(2021) Proof-of-concept study of multifunctional hybrid nanoparticle system combined with nir laser irradiation for the treatment of melanoma, Biomolecules 11(4), p. 511, MDPI, doi:10.3390/biom11040511
(2021) An update of advanced nanoplatforms for glioblastoma multiforme management, EXCLI Journal 20, p. 1544-1570, Leibniz Research Centre for Working Environment and Human Factors, doi:10.17179/excli2021-4393
(2021) An Overview on Ionic Liquids: A New Frontier for Nanopharmaceuticals, Nanopharmaceuticals: Principles and Applications Vol. 1, p. 181-204, Springer International Publishing, doi:10.1007/978-3-030-44925-4_5
(2021) Targeted delivery in scleroderma fibrosis, Autoimmunity Reviews 20(2), p. 102730, Elsevier, doi:10.1016/j.autrev.2020.102730
(2021) A newfangled collagenase inhibitor topical formulation based on ethosomes with sambucus nigra l. Extract, Pharmaceuticals 14(5), p. 467, MDPI, doi:10.3390/ph14050467
(2021) Dehydroabietic acid microencapsulation potential as biofilm-mediated infections treatment, Pharmaceutics 13(6), p. 825, MDPI, doi:10.3390/pharmaceutics13060825
(2021) Metabolomic profile and biological properties of sea lavender (Limonium algarvense erben) plants cultivated with aquaculture wastewaters: Implications for its use in herbal formulations and food additives, Foods 10(12), p. 3104, MDPI, doi:10.3390/foods10123104
(2021) Nanogold-based materials in medicine: From their origins to their future, Nanomedicine 16(30), p. 2695-2723, Future Medicine Ltd London, UK, doi:10.2217/nnm-2021-0265
(2021) The challenging melanoma landscape: From early drug discovery to clinical approval, Cells 10(11), p. 3088, MDPI, doi:10.3390/cells10113088
(2021) Therapeutic Implications of Nanopharmaceuticals in Skin Delivery, Nanopharmaceuticals: Principles and Applications Vol. 1, p. 205-272, Springer International Publishing, doi:10.1007/978-3-030-44925-4_6
(2021) Development of a topical insulin polymeric nanoformulation for skin burn regeneration: An experimental approach, International Journal of Molecular Sciences 22(8), p. 4087, MDPI, doi:10.3390/ijms22084087
(2021) Screening the dermatological potential of plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase, Journal of Enzyme Inhibition and Medicinal Chemistry 36(1), p. 257-269, Georg Thieme Verlag KG, doi:10.1080/14756366.2020.1862099
(2021) Natural Products and Nanopharmaceuticals, Nanopharmaceuticals: Principles and Applications Vol. 2, p. 113-154, Springer International Publishing, doi:10.1007/978-3-030-44921-6_4
(2021) Noncovalent Interactions with PAMAM and PPI Dendrimers Promote the Cellular Uptake and Photodynamic Activity of Rose Bengal: The Role of the Dendrimer Structure, Journal of Medicinal Chemistry 64(21), p. 15758-15771, American Chemical Society, doi:10.1021/acs.jmedchem.1c01080
(2021) A comprehensive updated review on magnetic nanoparticles in diagnostics, Nanomaterials 11(12), p. 3432, MDPI, doi:10.3390/nano11123432
(2021) Recent advances in nanogels in drug delivery systems, International Journal of Pharmaceutical Sciences and Nanotechnology 14(1), p. 5278-5286, Scientific Research Publishing, doi:10.37285/ijpsn.2021.14.1.3
(2021) Recent advances in ionic liquids and nanotechnology for drug delivery, Nanomedicine 16(1), p. 63-80, Future Medicine Ltd London, UK, doi:10.2217/nnm-2020-0340
(2021) Safety and efficacy assessment of aerogels for biomedical applications, Biomedicine and Pharmacotherapy 144, p. 112356, Elsevier Masson, doi:10.1016/j.biopha.2021.112356
(2021) Gold-based nanoplataform for the treatment of anaplastic thyroid carcinoma: A step forward, Cancers 13(6), p. 1-24, MDPI, doi:10.3390/cancers13061242
(2021) Oral insulin delivery: Utopia, currently possible or a near reality?, Therapeutic Delivery 12(6), p. 477-488, Newlands Press Ltd London, UK, doi:10.4155/tde-2021-0021
(2021) Superparamagnetic Ag-Fe3O4 composites nanoparticles for magnetic fluid hyperthermia, Journal of Magnetism and Magnetic Materials 537, p. 168242, North-Holland, doi:10.1016/j.jmmm.2021.168242
(2021) A Step Forward in Breast Cancer Research: Gold Nanoparticles as Photothermal Therapy Enhancers, AERoGELS COST Action (CA18125)
(2021) The latest developments in the area of therapeutic delivery excluding some diseases, such as COVID-19 and the big three (HIV/AID, malaria and tuberculosis), Therapeutic Delivery 12(12), p. 799-805, Newlands Press Ltd London, UK, doi:10.4155/tde-2021-0066
(2021) A Step Forward in Breast Cancer Research: a Preliminary Photothermal Approach Using Gold Nanoparticles, Book of abstracts iMedUlisboa
(2021) Self-assembly nanoparticles of natural bioactive abietane diterpenes, International Journal of Molecular Sciences 22(19), p. 10210, MDPI, doi:10.3390/ijms221910210
(2020) A step forward in breast cancer research: From a natural-like experimental model to a preliminary photothermal approach, International Journal of Molecular Sciences 21(24), p. 1-28, MDPI, doi:10.3390/ijms21249681
(2020) Novel and revisited approaches in nanoparticle systems for buccal drug delivery, Journal of Controlled Release 320, p. 125-141, Elsevier, doi:10.1016/j.jconrel.2020.01.006
(2020) A novel hybrid nanosystem integrating cytotoxic and magnetic properties as a tool to potentiate melanoma therapy, Nanomaterials 10(4), p. 693, MDPI, doi:10.3390/nano10040693
(2020) Anti-migratory and pro-apoptotic properties of parvifloron d on triple-negative breast cancer cells, Biomolecules 10(1), p. 158, MDPI, doi:10.3390/biom10010158
(2020) If you cannot beat them, join them: Exploring the fruits of the invasive species Carpobrotus edulis (L.) N.E. Br as a source of bioactive products, Industrial Crops and Products 144, p. 112005, Elsevier, doi:10.1016/j.indcrop.2019.112005
(2020) Green extraction of Sambucus nigra L. For potential application in skin nanocarriers, Green Materials 8(4), p. 181-193, Thomas Telford Ltd, doi:10.1680/jgrma.18.00074
(2020) Synchronous insight of in vitro and in vivo biological activities of Sambucus nigra L. extracts for industrial uses, Industrial Crops and Products 154, p. 112709, Elsevier, doi:10.1016/j.indcrop.2020.112709
(2020) Growth performance, in vitro antioxidant properties and chemical composition of the halophyte Limonium algarvense Erben are strongly influenced by the irrigation salinity, Industrial Crops and Products 143, p. 111930, Elsevier, doi:10.1016/j.indcrop.2019.111930
(2020) Anaplastic thyroid cancer: How far can we go?, EXCLI Journal 19, p. 800-812, Leibniz Research Centre for Working Environment and Human Factors, doi:10.17179/excli2020-2257
(2020) Royleanone Derivatives From Plectranthus spp. as a Novel Class of P-Glycoprotein Inhibitors, Frontiers in Pharmacology 11, p. 557789, Frontiers Media SA, doi:10.3389/fphar.2020.557789
(2020) Unveiling the mechanism of action of 7α-acetoxy-6β-hydroxyroyleanone on an mrsa/visa strain: Membrane and cell wall interactions, Biomolecules 10(7), p. 1-17, MDPI, doi:10.3390/biom10070983
(2020) Further evidence of possible therapeutic uses of sambucus nigra l. Extracts by the assessment of the in vitro and in vivo anti-inflammatory properties of its plga and pcl-based nanoformulations, Pharmaceutics 12(12), p. 1-28, MDPI, doi:10.3390/pharmaceutics12121181
(2020) Nanomaterials in wound healing: From material sciences to wound healing applications, Nano Select 1(5), p. 443-460, doi:10.1002/nano.202000055
(2020) Preliminary assays towards melanoma cells using phototherapy with gold-based nanomaterials, Nanomaterials 10(8), p. 1-14, MDPI, doi:10.3390/nano10081536
(2020) Nanotechnology for oral drug delivery and targeting, Nanoengineered Biomaterials for Advanced Drug Delivery, p. 473-498, CRC Press, doi:10.1016/B978-0-08-102985-5.00020-6
(2020) How can biomolecules improve mucoadhesion of oral insulin? A comprehensive insight using ex-vivo, in silico, and in vivo models, Biomolecules 10(5), p. 675, MDPI, doi:10.3390/biom10050675
(2020) Assessment of the potential skin application of Plectranthus ecklonii benth., Pharmaceuticals 13(6), p. 1-10, MDPI, doi:10.3390/ph13060120
(2020) Experimental models as refined translational tools for breast cancer research, Scientia Pharmaceutica 88(3), p. 1-29, MDPI, doi:10.3390/scipharm88030032
(2019) Combination of hyaluronic acid and PLGA particles as hybrid systems for viscosupplementation in osteoarthritis, International Journal of Pharmaceutics 559, p. 13-22, Elsevier, doi:10.1016/j.ijpharm.2019.01.017
(2019) Parvifloron D from plectranthus strigosus: Cytotoxicity screening of Plectranthus spp. extracts, Biomolecules 9(10), p. 616, MDPI, doi:10.3390/biom9100616
(2019) Optimization of nanostructured lipid carriers loaded with retinoids by central composite design, Journal of Molecular Liquids 293, p. 111468, Elsevier, doi:10.1016/j.molliq.2019.111468
(2019) Development and mechanistic insight into the enhanced cytotoxic potential of parvifloron D albumin nanoparticles in EGFR-overexpressing pancreatic cancer cells, Cancers 11(11), p. 1733, MDPI, doi:10.3390/cancers11111733
(2019) Naturally Occurring Plectranthus-derived Diterpenes with Antitumoral Activities, Current Pharmaceutical Design 24(36), p. 4207-4236, Bentham Science Publishers, doi:10.2174/1381612825666190115144241
(2019) Current trends in cancer nanotheranostics: metallic, polymeric, and lipid-based systems, Pharmaceutics 11(1), p. 22, MDPI
(2019) Cytotoxic Activity of Royleanone Diterpenes from Plectranthus madagascariensis Benth, ACS Omega 4(5), p. 8094-8103, American Chemical Society, doi:10.1021/acsomega.9b00512
(2019) Comparison study of different extracts of plectranthus madagascariensis, p. Neochilus and the rare p. porcatus (lamiaceae): Chemical characterization, antioxidant, antimicrobial and cytotoxic activities, Biomolecules 9(5), p. 179, MDPI, doi:10.3390/biom9050179
(2019) Phytosomes with persimmon (Diospyros kaki l.) extract: Preparation and preliminary demonstration of in vivo tolerability, Pharmaceutics 11(6), doi:10.3390/pharmaceutics11060296
(2019) An industry update in therapeutics: What is the latest news?, Therapeutic Delivery 10(7), p. 401-407, Future Science Ltd London, UK, doi:10.4155/tde-2019-0026
(2019) An industry update in therapeutics: What is the latest news?, Therapeutic Delivery 10(7), p. 401-407, Newlands Press Ltd London, UK, doi:10.4155/tde-2019-0026
(2019) Phytosomes with persimmon (Diospyros kaki l.) extract: Preparation and preliminary demonstration of in vivo tolerability, Pharmaceutics 11(6), p. 296, MDPI, doi:10.3390/pharmaceutics11060296
(2018) Extraction Optimization and Structural and Thermal Characterization of the Antimicrobial Abietane 7α-Acetoxy-6β-hydroxyroyleanone, Molecular Pharmaceutics 15(4), p. 1412-1419, American Chemical Society, doi:10.1021/acs.molpharmaceut.7b00892
(2018) Development of parvifloron D-loaded smart nanoparticles to target pancreatic cancer, Pharmaceutics 10(4), doi:10.3390/pharmaceutics10040216
(2018) Anaplastic thyroid cancer, Practical Management of Thyroid Cancer: A Multidisciplinary Approach, p. 297-305, IfADo-Leibniz Research Centre for Working Environment and Human Factors~'85, doi:10.1007/978-3-319-91725-2_22
() P-086 Alginate beads for transdermal drug delivery: II-In vitro permeation studies
(2018) Supercritical CO2 extracts and volatile oil of basil (Ocimum basilicum L.) comparison with conventional methods, Separations 5(2), p. 21, MDPI, doi:10.3390/separations5020021
(2018) Diterpenes from Plectranthus spp.: a ROS-induced cytotoxicity study, Free Radical Biology and Medicine 120, p. S127, Pergamon, doi:10.1016/j.freeradbiomed.2018.04.419
(2018) Anti-tumor properties of the redox-active compound Parvifloron D in breast cancer cells, Free Radical Biology and Medicine 120, p. S119-S120, Pergamon, doi:10.1016/j.freeradbiomed.2018.04.394
(2018) Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies, European Polymer Journal 104, p. 19-31, Pergamon, doi:10.1016/j.eurpolymj.2018.04.032
(2018) Anticancer properties of the abietane diterpene 6, 7-dehydroroyleanone obtained by optimized extraction, Future Medicinal Chemistry 10(10), p. 1177-1189, Future Science Ltd London, UK, doi:10.4155/fmc-2017-0239
(2018) Mitochondrial dysfunction of halimane and labdane diterpenes in human lung cancer cells, Free Radical Biology and Medicine 120, p. S130, Pergamon, doi:10.1016/j.freeradbiomed.2018.04.429
(2018) Rosmarinus officinalis L.: An update review of its phytochemistry and biological activity, Future Science OA 4(4), p. FSO283, Future Science Ltd London, UK, doi:10.4155/fsoa-2017-0124
(2018) Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species, Future Medicinal Chemistry 10(14), p. 1677-1691, Georg Thieme Verlag KG, doi:10.4155/fmc-2018-0043
(2018) Mucoadhesive assessment of different antifungal nanoformulations, Bioinspiration and Biomimetics 13(5), p. 55001, IOP Publishing, doi:10.1088/1748-3190/aad488
(2018) Antitubercular and anti-inflammatory properties screening of natural products from Plectranthus species, Future Medicinal Chemistry 10(14), p. 1677-1691, Future Science Ltd London, UK, doi:10.4155/fmc-2018-0043
() Development of an analytical method for the determination of hyaluronic acid encapsulated in polymeric nanoparticles
(2018) Melanoma Prevention: Challenges and Progresses in Nanotechnology for Melanoma Prevention and Treatment, CRC Concise Encyclopedia of Nanotechnology, p. 480-497, doi:10.1201/b19457-43
(2018) Development of a bioadhesive nanoformulation with Glycyrrhiza glabra L. extract against Candida albicans, Biofouling 34(8), p. 880-892, Taylor & Francis, doi:10.1080/08927014.2018.1514391
(2018) Design and evaluation of novel topical formulation with olive oil as natural functional active, Pharmaceutical Development and Technology 23(8), p. 794-805, Taylor & Francis, doi:10.1080/10837450.2017.1340951
() Aim: To produce and characterize different types of nanoparticles for cosmetic purposes.
(2018) Development of parvifloron D-loaded smart nanoparticles to target pancreatic cancer, Pharmaceutics 10(4), p. 216, MDPI, doi:10.3390/pharmaceutics10040216
(2017) Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia, Skin Pharmacology and Physiology 30(4), p. 197-204, S. Karger AG, doi:10.1159/000475473
(2017) Biological activity screening of seven Plectranthus species, Journal Biomedical and Biopharmaceutical Research 14(1), p. 95-108, doi:10.19277/bbr.14.1.153
(2017) Nanotechnological strategies for nerve growth factor delivery: Therapeutic implications in Alzheimer's disease, Pharmacological Research 120, p. 68-87, Academic Press, doi:10.1016/j.phrs.2017.03.020
(2017) Past, Recent Progresses and Future Perspectives of Nanotechnology Applied to Antifungal Agents, Current Drug Metabolism 18(4), p. 280-290, Bentham Science Publishers, doi:10.2174/1389200218666170201152000
(2017) Nanosystems for Skin Delivery: From Drugs to Cosmetics, Current Drug Metabolism 18(5), p. 412-425, Bentham Science Publishers, doi:10.2174/1389200218666170306103101
(2017) Broad overview of engineering of functional nanosystems for skin delivery, International Journal of Pharmaceutics 532(2), p. 710-728, Elsevier, doi:10.1016/j.ijpharm.2017.07.078
(2017) An emerging integration between ionic liquids and nanotechnology: General uses and future prospects in drug delivery, Therapeutic Delivery 8(6), p. 461-473, Future Science Ltd London, UK, doi:10.4155/tde-2017-0002
(2017) Phytosomes as Biocompatible Carriers of Natural Drugs, Current Medicinal Chemistry 24(6), p. 568-589, Bentham Science Publishers, doi:10.2174/0929867323666161028160855
(2017) Biological activity screening of seven Plectranthus species Pesquisa de actividade biológica de sete espécies de Plectranthus, Biopharmaceutical Sciences│Ciências Biofarmacêuticas Biomed Biopharm Res 1(14), p. 95-108, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas, url
(2017) Pancreatic Cancer Therapy Review: From Classic Therapeutic Agents to Modern Nanotechnologies, Current Drug Metabolism 18(4), p. 346-359, Bentham Science Publishers, doi:10.2174/1389200218666170201151135
() Contribution O4-2
(2016) Antioxidant activity and rosmarinic acid content of ultrasound-assisted ethanolic extracts of medicinal plants, Measurement: Journal of the International Measurement Confederation 89, p. 328-332, Elsevier, doi:10.1016/j.measurement.2016.04.033
(2016) Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies, ChemMedChem 11(18), p. 2015-2023, doi:10.1002/cmdc.201600244
(2016) Reactivity of Diterpenoid Quinones: Royleanones., Current Pharmaceutical Design 22(12), p. 1682-1714, Bentham Science Publishers, doi:10.2174/1381612822666151211094521
(2016) Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy, Studies in Natural Products Chemistry 50, p. 45-79, Elsevier, doi:10.1016/B978-0-444-63749-9.00002-5
(2016) Lectin-coated particulate delivery systems for oral administration, Advances and Challenges in Oral Delivery of Macromolecules, p. 108-121, doi:10.4155/fseb2013.13.109
(2016) Plectranthus madagascariensis e P . neochilus Pesquisa de actividade antimicrobiana em extractos de Plectranthus madagascariensis e P . neochilus, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas
(2016) Functionalized diterpene parvifloron D-loaded hybrid nanoparticles for targeted delivery in melanoma therapy, Therapeutic Delivery 7(8), p. 521-544, Future Science Ltd London, UK, doi:10.4155/tde-2016-0027
(2016) EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy, PLoS ONE 11(10), p. e0165419, Public Library of Science San Francisco, CA USA, doi:10.1371/journal.pone.0165419
(2016) Choline-Based Ionic Liquids: Improvement of Antimicrobial Activity, ChemistrySelect 1(18), p. 5909-5916, doi:10.1002/slct.201600864
(2016) Innovative formulation of nystatin particulate systems in toothpaste for candidiasis treatment, Pharmaceutical Development and Technology 21(3), p. 282-287, Taylor & Francis, doi:10.3109/10837450.2014.999783
(2016) Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents, Expert Opinion on Drug Delivery 13(8), p. 1133-1148, Taylor & Francis, doi:10.1080/17425247.2016.1178233
(2016) An Overview of Pharmaceutical Excipients: Safe or Not Safe?, Journal of Pharmaceutical Sciences 105(7), p. 2019-2026, Elsevier, doi:10.1016/j.xphs.2016.03.019
(2016) Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation, Drug Development and Industrial Pharmacy 42(10), p. 1695-1699, Taylor & Francis, doi:10.3109/03639045.2016.1165692
(2016) Bioproduction of gold nanoparticles for photothermal therapy, Therapeutic Delivery 7(5), p. 287-304, Future Science Ltd London, UK, doi:10.4155/tde-2015-0011
(2015) Good manufacturing practices for medicinal products for human use, Journal of Pharmacy and Bioallied Sciences 7(2), p. 87-96, Wolters Kluwer--Medknow Publications, doi:10.4103/0975-7406.154424
(2015) Cytotoxicity screening of Plectranthus spp. extracts and individual components in MDA-MB-231 cells, Toxicology Letters 238(2), p. S240, doi:10.1016/j.toxlet.2015.08.707
(2015) Synthesis and characterization of S-nitrosoglutathione-oligosaccharide-chitosan as a nitric oxide donor, Expert Opinion on Drug Delivery 12(8), p. 1209-1223, Informa Healthcare, doi:10.1517/17425247.2015.1028916
(2015) Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts, Journal Biomedical and Biopharmaceutical Research 12(1), p. 127-138, doi:10.19277/bbr.12.1.111
(2015) Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment, International Journal of Pharmaceutics 493(1-2), p. 271-284, Elsevier, doi:10.1016/j.ijpharm.2015.07.044
(2015) Lysozyme photochemistry as a function of temperature. the protective effect of nanoparticles on lysozyme photostability, PLoS ONE 10(12), p. e0144454, Public Library of Science San Francisco, CA USA, doi:10.1371/journal.pone.0144454
(2015) A novel topical association with zinc oxide, chamomile and aloe vera extracts - stability and safety studies, Journal Biomedical and Biopharmaceutical Research 12(2), p. 251-264, doi:10.19277/bbr.12.2.122
(2015) Plectranthus madagascariensis phytosomes: formulation optimization, Journal Biomedical and Biopharmaceutical Research 12(2), p. 223-231, doi:10.19277/bbr.12.2.119
(2015) Antimicrobial screening of Plectranthus madagascariensis and P. neochilus extracts, Journal Biomedical and Biopharmaceutical Research 12(1), p. 127-138, doi:10.19277/bbr.12.1.111
(2015) Hybrid nanoparticles for photodynamic and targeted cancer therapy: Cytotoxicity studies, Toxicology Letters 238(2), p. S204, doi:10.1016/j.toxlet.2015.08.611
(2015) Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders, Measurement: Journal of the International Measurement Confederation 74, p. 170-177, Elsevier, doi:10.1016/j.measurement.2015.07.029
(2015) Uma nova associação de uso tópico contendo óxido de zinco e extractos de aloe vera e camomila-estudos de estabilidade e segurança, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas, url
(2015) Fitossomas de Plectranthus madagascariensis: otimiza{c{c}}{~a}o da formula{c{c}}{~a}o, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas
() Encapsulation Of Diterpene Parvifloron D In Hybrid Nanoparticles For Cancer Targeted Therapy
(2014) Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin, Polymers 6(2), p. 479-490, MDPI, doi:10.3390/polym6020479
(2014) Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment, Drug Development and Industrial Pharmacy 40(3), p. 409-417, Taylor & Francis, doi:10.3109/03639045.2013.767826
(2014) Drug Nanocarriers based on Biomacromolecules: How far we’ve Come?, Nanotechnology 11(January 2014), p. 484, url
(2014) Ibuprofen Nanoparticles for Oral Delivery: Proof of Concept, Journal of Nanomedicine & Biotherapeutic Discovery 04(01), p. 1, OMICS Publishing Group, doi:10.4172/2155-983x.1000119
(2014) Abietane diterpenes from Plectranthus madagascariensis: A cytotoxicity screening, Planta Medica 80(16), p. P1L152, doi:10.1055/s-0034-1394809
(2014) Optimiza{c{c}}{~a}o da efici{^e}ncia de encapsula{c{c}}{~a}ode um novo nanosistema para a administra{c{c}}{~a}o oral de insulina, Edi{c{c}}{~o}es Lus{'o}fonas
(2014) Optimization of medicinal plant extraction methods and their encapsulation through extrusion technology, Measurement: Journal of the International Measurement Confederation 58, p. 249-255, Elsevier, doi:10.1016/j.measurement.2014.08.045
(2014) Nanopart{'i}culas de PCL com acetato de hidrocortisona como uma terapia dermatol{'o}gica inovadora para a dermatite at{'o}pica
(2014) Oral delivery of biopharmaceuticals, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies 9781461495, p. 125-147, Springer US, doi:10.1007/978-1-4614-9524-6_5
(2014) Optimization of the encapsulation efficiency of a novel oral insulin delivery nanosystem, Journal Biomedical and Biopharmaceutical Research 11(1), p. 111-119, doi:10.19277/bbr.11.1.82
(2013) Drug carriers for oral delivery of peptides and proteins: Accomplishments and future perspectives, Therapeutic Delivery 4(2), p. 251-265, Future Science Ltd London, UK, doi:10.4155/tde.12.143
(2013) Hydrocortisone acetate-loaded PCL nanoparticles as an innovative dermatological therapy for atopic dermatitis, Journal Biomedical and Biopharmaceutical Research 10(1), p. 73-82, doi:10.19277/bbr.10.1.53
(2013) Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles, Microscopy and Microanalysis 19(5), p. 1141-1150, Cambridge University Press, doi:10.1017/S1431927613000536
(2013) A nanotecnologia aplicada {`a} veicula{c{c}}{~a}o de f{'a}rmacos: estudos de desenvolvimento da formula{c{c}}{~a}o e caracteriza{c{c}}{~a}o
(2013) Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles, Microscopy and Microanalysis 19(5), p. 1141-1150, Oxford University Press, doi:10.1017/S1431927613000536
(2013) Influência de duas técnicas diferentes no tamanho e potencial zeta de nanopartículas de poli (DL-láctico-co-glicólico)., Rev Lusófona de Ciências e Tecnologias da Saúde 8(2), p. 329-338, url
(2013) Hydrocortisone-loaded poly(ε-caprolactone) nanoparticles for atopic dermatitis treatment, Pharmaceutical Development and Technology 18(3), p. 710-718, Taylor & Francis, doi:10.3109/10837450.2012.712537
(2013) Controlo microbiol{'o}gico de formula{c{c}}{~o}es farmac{^e}uticas parent{'e}ricas
(2012) Effects of an oral insulin nanoparticle administration on hepatic glucose metabolism assessed by 13C and 2H isotopomer analysis, Journal of Microencapsulation 29(2), p. 167-176, Taylor & Francis, doi:10.3109/02652048.2011.638992
(2012) Nanotechnology as a promising strategy for alternative routes of insulin delivery, Methods in Enzymology 508, p. 271-294, Academic Press, doi:10.1016/B978-0-12-391860-4.00014-8
(2011) Hydrocortisone Nanoparticles for Atopic Dermatitis Treatment, SOFW- Journal 137(8), p. 2-7
() P-069 Development and in vitro characterization of drug-loaded gelatin nanosystem
(2011) Design and Transdermal Delivery of Indomethacin Nanosystem, Journal of Materials Science and Engineering A 1(4A), p. 531-537, David Publishing Company, Inc.
(2011) Hydrocortisone Nanoparticles for Atopic Dermatitis Treatment, SOFW- Journal 137(8), p. 2-7
(2011) Design and Transdermal Delivery of Indomethacin Nanosystem, Journal of Materials Science and Engineering A 1, p. 531-537
(2010) Influ{^e}ncia do sistema de liberta{c{c}}{~a}o na permea{c{c}}{~a}o de uma mol{'e}cula hidrof{'i}lica, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas
(2010) Conclusions & Perspectives
(2009) O40 Administration orale d’insuline : vers une nouvelle approche, Diabetes & Metabolism 35, p. A11, Elsevier Masson, doi:10.1016/s1262-3636(09)71732-x
(2008) Nanoparticle strategies for the oral delivery of insulin, Expert Opinion on Drug Delivery 5(1), p. 45-68, Taylor & Francis, doi:10.1517/17425247.5.1.45
(2008) Nanoparticulate biopolymers deliver insulin orally eliciting pharmacological response, Journal of Pharmaceutical Sciences 97(12), p. 5290-5305, Elsevier, doi:10.1002/jps.21347
() P11-014, Evaluation 11, p. 17
(2008) Polyelectrolyte biomaterial interactions provide nanoparticulate carrier for oral insulin delivery, Drug Delivery 15(2), p. 127-139, Taylor & Francis, doi:10.1080/10717540801905165
(2008) Toxicological assessment of orally delivered nanoparticulate insulin, Nanotoxicology 2(4), p. 205-217, Taylor & Francis, doi:10.1080/17435390802398309
(2008) Novas Alternativas Terapêuticas Para a Adminitração Oral da Insulina Novel therapeutic strategies for oral administration of insulin, Revista Lusófona de Ciências e Tecnologias da Saúde(5), p. 174-205, Edi{c{c}}{~o}es Universit{'a}rias Lus{'o}fonas
(2007) Toxicological in vivo studies of an oral insulin nanosystem, Toxicology Letters 172, p. S90, doi:10.1016/j.toxlet.2007.05.250
(2007) Nanoparticulate delivery system for insulin: Design, characterization and in vitro/in vivo bioactivity, European Journal of Pharmaceutical Sciences 30(5), p. 392-397, Elsevier, doi:10.1016/j.ejps.2006.12.007
(2007) Alginate microparticles as novel carrier for oral insulin delivery, Biotechnology and Bioengineering 96(5), p. 977-989, Wiley Subscription Services, Inc., A Wiley Company Hoboken, doi:10.1002/bit.21164
(2006) Biology, Medicine, Nanoencapsulation I. Methods for preparation of drugloaded polymeric nanoparticles 2(1), p. 8-21
(2006) Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine 2(1), p. 8-21, Elsevier, doi:10.1016/j.nano.2005.12.003
(2006) Ribeiro, A. n. J.; Veiga, F, Nanomedicine: Nanotechnology, Biology and Medicine 2(1), p. 8-21
(2006) Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems, Nanomedicine: Nanotechnology, Biology, and Medicine 2(2), p. 53-65, Elsevier, doi:10.1016/j.nano.2006.04.009
() P-083 Alginate beads for transdermal drug delivery: I--Design and characterization studies
(2006) Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine 2(1), p. 8-21, doi:10.1016/j.nano.2005.12.003
(2006) Metoda za inkapsulaciju insulina u alginatne nanokapsule: Uticaj kalcijum jona na ponašanje dobijenih kapsula, Chemical Industry and Chemical Engineering Quarterly 12(1), p. 47-52, doi:10.2298/CICEQ0601047R
(2006) Nanomedicine: Nanotechnology, Biol Med 2(1), p. 8e21
(2006) Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine 2(1), p. 8-21, doi:10.1016/j.nano.2005.12.003
(2006) Review and current status of emulsion/dispersion technology using an internal gelation process for the design of alginate particles, Journal of Microencapsulation 23(3), p. 245-257, Taylor & Francis, doi:10.1080/02652040500286086
(2005) Diagnostic investigation and multidisciplinary management in motor neuron disease, Journal of Neurology 252(12), p. 1435-1447, Steinkopff-Verlag, doi:10.1007/s00415-005-0007-9
(2003) Aspects of distribution, transport and recruitment of Alaska plaice (Pleuronectes quadrituberculatus) in the Gulf of Alaska and eastern Bering Sea: comparison of marginal and central populations KM Bailey, ES Brown and JT Duffy-Anderson..................., Journal of Sea Research 50, p. 331-332
(1998) Nasopharynx carcinoma stadium: CT and MR evaluation; Estadiamento dos carcinomas da nasofaringe. Avaliacao por TC e RM, Radiologia Brasileira (Rio de Janeiro) 31
(1998) Oropharynx carcinoma stadium: CT and MR evaluation, Radiologia Brasileira 31(2), p. 126
(1988) A new surgical method to treat reflux gastritis and prevent gastric carcinoma, Acta medica portuguesa 1(1), p. 9-15
Conference publications
(2021) Gold nanoparticles as a part of a photothermal therapy system.
(2019) Kleefstra syndrome: A case report of a rare genetic disorder with an uncommon presentation, European Journal of Human Genetics 27(Supplement 2), p. 1878-1879, url
(2016) Multiple source phototherapy in breast cancer: A viability study, BIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016, p. 247-250, doi:10.5220/0005794902470250
(2015) Concentrated photoactivation: Focusing light through scattering, IFMBE Proceedings 51, p. 1727-1730, doi:10.1007/978-3-319-19387-8_419
(2014) Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms, Second International Conference on Applications of Optics and Photonics 9286, p. 92863Z, doi:10.1117/12.2063539
(2009) A new approach for oral delivery of insulin, Diabetologia 52(S1), p. S372, url
(2009) Oral administration of insulin: towards a new approach, Diabetes & Metabolism 35, p. A11--A11
(2007) Alginate-based insulin nanoparticles - dextrane for oral administration in the diabetic rat, Diabetes & Metabolism 33, p. S67-S67 WE - Science Citation Index Expanded (SCI
() A30-MAGNETITE NANOPARTICLES FOR MAGNETIC HYPERTHERMIA, Book of Abstracts, p. 80
(2004) Insulin-loaded alginate nanoparticles obtained by emulsification/internal gelation, "XIIth International Workshop on Bioencapsulation" 24, p. 26
Book chapters
(2023) Challenges in delivery of plant actives, Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products, p. 35-82, Academic Press, doi:10.1016/B978-0-323-99125-4.00008-1
(2022) Application of natural raw materials for development of cosmetics through nanotechnology, Nanotechnology for the Preparation of Cosmetics using Plant-Based Extracts, p. 157-201, Elsevier, doi:10.1016/B978-0-12-822967-5.00014-X
(2021) Advances in nanotechnology-related strategies against melanoma, Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine, p. 385-424, Academic Press, doi:10.1016/B978-0-323-85666-9.00009-7
(2020) Natural-based consumer health nanoproducts: Medicines, cosmetics, and food supplements, Handbook of Functionalized Nanomaterials for Industrial Applications, p. 527-578, Elsevier, doi:10.1016/B978-0-12-816787-8.00019-3
(2020) A new approach for cancer treatment: from specific induction of breast cancer to innovative gold-nanoparticle mediated thermal therapies, Nanomedicines for Breast Cancer Theranostics, p. 269-298, Elsevier, doi:10.1016/B978-0-12-820016-2.00012-4
(2017) In vivo tumor suppression efficacy of mesoporous silica nanoparticle-based drug delivery system: Enhanced efficacy by folate modification, Nanomedicine in Cancer, p. 215-234, Jenny Stanford Publishing, doi:10.1201/9781315114361