The paper “A computational model of tsDCS effects in SOD1 mice: from MRI-based design to validation” was recently published in the journal Computers in Biology and Medicine by PhD student Leonor de Oliveira Pires and IBEB researcher and professor Sofia Rita Fernandes.

The work was developed under the scope of the European consortium DC4MND (“Multidimensional mechanistic investigations of trans spinal direct current stimulation in motor neuron disease”), in collaboration with Bartosz Wasicki and Marcin Bączyk (University of Poznań, Poland), Alireza Abaei, Jelena Scekic-Zahirovic, and Francesco Roselli (University of Ulm, Germany).

The study presents a 3D computational model of a SOD1 mouse (an in vivo model of Amyotrophic Lateral Sclerosis) designed to predict the effects of trans-spinal direct current stimulation (tsDCS).


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