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Tumor Treating Fields (TTF)

The general aim of this project is to investigate the electric field produced in the brain during the application of tumor treating fields for the treatment of Glioblastoma multiforme. The specific aims are
1) To develop analytical and finite element (FE) mesh models describing the distribution of intermediate frequency electric fields within the brain.
2) To develop analytical and finite element models of the electric fields produced within cells in response to an applied AC electric field.
3) To use DTI data to incorporate anisotropy in the electrical conductivity (i.e., the electrical conductivity tensor) in white matter in the FE modeling framework.